Aphamea Brochure
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Oral Suspension
Each 5 mL of reconstituted suspension contains ampicillin ‎trihydrate equivalent to 125 mg ampicillin.‎

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Ampicillin and other ‎antibacterial drugs, it should be used only to treat or prevent infections that are proven or strongly suspected to be ‎caused by bacteria. When culture and susceptibility information are available, they should be considered in ‎selecting of modifying antimicrobial therapy, in the absence of such data, local epidemiology and susceptibility ‎patterns contribute to the empiric selection of therapy.‎
It is indicated in the treatment of infections caused by susceptible strains of the following organisms:‎
• Infections of the genitourinary tract including gonorrhea, E. coli, P. mirabilis, enterococci, Shigella, S. typhosa ‎and other Salmonella and non-penicillinase producing N. gonorrhoeae.‎
• Infections of the respiratory tract: Non-penicillinase producing H. influenzae and staphylococci, and ‎streptococci including Streptococcus pneumoniae.‎
• Infections of the gastrointestinal tract: Shigella, S. typhosa and other Salmonella, E. coli, P. mirabilis, and ‎enterococci.‎
• Meningitis: N. Meningitidis
Bacteriology studies to determine the causative organisms and their susceptibility to ampicillin should be ‎performed. Therapy may be instituted prior to the results of susceptibility testing.‎
Adults and children weighing over 20 Kg: ‎
‎1.‎ For genitourinary or gastrointestinal tract infections other than gonorrhea in men and women: the usual ‎dose is 500 mg q.i.d.‎
‎2.‎ For the treatment of gonorrhea in both men and women: a single oral dose of 3.5 grams of ampicillin ‎administered simultaneously with 1 gram of probenecid is recommended. ‎
Physicians are cautioned to use no less than the above recommended dosage for the treatment of ‎gonorrhea. Follow-up cultures should be obtained from the original site(s) of infection 7 to 14 days after ‎therapy.‎
In women, it is also desirable to obtain culture test-of-cure from both the endocervical and anal canals. ‎Prolonged intensive therapy is needed for complications such as prostatitis and epididymitis. ‎
‎3.‎ For respiratory tract infections: the usual dose is 250 mg q.i.d. ‎
Pediatric Patients weighing 20 Kg or less: ‎
‎1.‎ For genitourinary or gastrointestinal tract infections: the usual dose is 100 mg/kg/day, q.i.d. ‎
‎2.‎ For respiratory tract infections: the usual dose is 50 mg/kg/day, three to four times daily. Doses for children ‎should not exceed doses recommended for adults.‎
All patients, irrespective of age and weight larger doses may be required for severe or chronic infections. ‎
Except for the single dose regimen for gonorrhea, therapy should be continued for a minimum of 48 to 72 ‎hours after the patient becomes asymptomatic or evidence that bacterial eradication has been obtained. ‎
In infections caused by hemolytic strains of streptococci, a minimum of 10 days' treatment is recommended to ‎guard against the risk of rheumatic fever or glomerulonephritis
Stubborn infections may require treatment for several weeks
The patient should inform the physician of any history of sensitivity to allergens, including previous ‎hypersensitivity reactions to penicillins and cephalosporins ‎
The patient should discontinue ampicillin and contact the physician immediately if any side effect occurs ‎
Ampicillin should be taken with a full glass of water, one-half hour before or two hours after meals for ‎maximal absorption.‎
Diabetic patients should consult with the physician before changing diet or dosage of diabetes medication. ‎
Patients should be counseled that antibacterial drugs should only be used to treat bacterial infections. They do ‎not treat viral infections.‎
When Ampicillin prescribed to treat a bacterial infection, patients should be told that, although it is common to ‎feel better early in the course of therapy, the medication should be taken exactly as directed. ‎
Skipping doses or not completing the full course of therapy may:‎
o Decrease the effectiveness of the immediate treatment.‎
o Increase the likelihood that bacteria will develop resistance and will not be treatable by Ampicillin or other ‎antibacterial drugs in the future